Assembly Mechanism of FCT Region Type 1 Pili in Serotype M6 Streptococcus pyogenes*
نویسندگان
چکیده
منابع مشابه
Involvement of T 6 pili in biofilm formation by serotype M 6 Streptococcus 1 pyogenes
Involvement of T6 pili in biofilm formation by serotype M6 Streptococcus 1 pyogenes 2 3 4 Keiji Richard Kimura , Masanobu Nakata , Tomoko Sumitomo, Bernd Kreikemeyer, 5 Andreas Podbielski, Yutaka Terao, and Shigetada Kawabata* 6 7 8 Department of Oral and Molecular Microbiology, Osaka University Graduate School of 9 Dentistry, 1-8, Yamadaoka, Suita, Osaka, 565-0871, Japan. 10 Institute of Medic...
متن کاملMode of expression and functional characterization of FCT-3 pilus region-encoded proteins in Streptococcus pyogenes serotype M49.
The human pathogen Streptococcus pyogenes (group A streptococcus [GAS]) pilus components, suggested to play a role in pathogenesis, are encoded in the variable FCT (fibronectin- and collagen-binding T-antigen) region. We investigated the functions of sortase A (SrtA), sortase C2 (SrtC2), and the FctA protein of the most prevalent type 3 FCT region from a serotype M49 strain. Although it is cons...
متن کاملMolecular mechanism of bacterial type 1 and P pili assembly.
The formation of adhesive surface structures called pili or fimbriae ('bacterial hair') is an important contributor towards bacterial pathogenicity and persistence. To fight often chronic or recurrent bacterial infections such as urinary tract infections, it is necessary to understand the molecular mechanism of the nanomachines assembling such pili. Here, we focus on the so far best-known pilus...
متن کاملPopulation genetics and linkage analysis of loci within the FCT region of Streptococcus pyogenes.
The FCT regions of Streptococcus pyogenes strains encode a variety of cell wall-anchored surface proteins that bind the extracellular matrix of the human host and/or give rise to pilus-like appendages. Strong linkage is evident between transcription-regulatory loci positioned within the FCT and emm regions and the emm pattern genotype marker for preferred infection of the throat or skin. These ...
متن کاملInvolvement of T 6 pili in biofilm formation by serotype M 6 Streptococcus 1 pyogenes 2 3 4 Keiji
Involvement of T6 pili in biofilm formation by serotype M6 Streptococcus 1 pyogenes 2 3 4 Keiji Richard Kimura , Masanobu Nakata , Tomoko Sumitomo, Bernd Kreikemeyer, 5 Andreas Podbielski, Yutaka Terao, and Shigetada Kawabata* 6 7 8 Department of Oral and Molecular Microbiology, Osaka University Graduate School of 9 Dentistry, 1-8, Yamadaoka, Suita, Osaka, 565-0871, Japan. 10 Institute of Medic...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 2011
ISSN: 0021-9258
DOI: 10.1074/jbc.m111.239780